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. 2016 Mar 1;13:35. doi: 10.1186/s12985-016-0494-6

Fig. 6.

Fig. 6

Inhibition of NS5 phosphorylation by PKC promotes viral replication. PKC is a host factor, which restricts intracellular DENV2 number by phosphorylating viral NS5. Inhibition of PKC by PKC inhibitor (BisI) or PKC-specific siRNA (siPKC) results in increased viral copy number