Table II.

Levels of IL-6 in the plasma and lung tissue of rats in groups A-D.

Indices	Group A	Group B	Group C	Group D
IL-6 in plasma (µg/l)	103.83±32.14	157.48±39.59a	178.53±45.78a,b	194.91±54.59a,b,c
IL-6 in lung tissue (µg/l)	97.58±31.67	117.79±35.54	146.60±43.81d,e	162.80±46.01d,e,f

Levels of IL-6 in plasma are significantly increased in the rats in groups B-D, as compared with group A; whereas levels of IL-6 in the lung tissue are significantly increased in the rats in groups C and D, as compared with group A. Group A, normal group; group B, acute pulmonary edema model induced by hypoxia for 24 h; group C, acute pulmonary edema model induced by hypoxia for 48 h; and group D, acute pulmonary edema model induced by hypoxia for 72 h.

^aP<0.05, vs. group A plasma

^bP<0.05, vs. group B plasma

^cP<0.05, vs. group C plasma

^dP<0.05, vs. group A lung tissue

^eP<0.05, vs. group B lung tissue

^fP<0.05, vs. group C lung tissue.