Figure 1.

Detection of components of the biofilm matrix from Staphylococcus aureus-infected wounds with and without NPWT treatment. NPWT resulted in significant reductions in (A) PIA and (B) eDNA content relative to untreated wounds. *P<0.05 and **P<0.01 vs. untreated control. Data are presented as mean ± standard deviation (n=10–12 wounds/group). NPWT, negative pressure wound therapy; PIA, polysaccharide intercellular adhesin; eDNA, extracellular DNA; A₅₈₅, absorbance at 585 nm.