Table III.
Genotypes frequency of OPN rs1126616 polymorphism in SLE patients with and without LN.
| OPN rs1126616 | SLE patients with LN n=36 | SLE patients without LN n=127 | Controls n=180 | P-valuea | OR (95% CI)a | P-valueb | OR (95% CI)b |
|---|---|---|---|---|---|---|---|
| Genotypes, n (%) | |||||||
| CC | 17 (47) | 94 (74) | 138 (77) | 1 | 1 | ||
| CT | 17 (47) | 30 (24) | 40 (22) | 0.004 | 3.1 (1.4–6.9) | 0.001 | 3.5 (1.6–7.4) |
| TT | 2 (6) | 3 (2) | 2 (1) | 0.170 | 3.7 (0.6–23.7) | 0.043 | 8.1 (1.1–62.5) |
a
Between SLE patients with LN and without LN
b
between SLE patients with LN and controls. SLE, systemic lupus erythematosus; OPN, osteopontin; OR, odds ratio; CI, confidence interval; LN, lupus nephritis.