Table I.
Detection of AQP4 protein expression levels in brain tissues of the various treatment groups by SABC immunohistochemistry (OD values; n=6).
| Region | CK group | HH group | CU group | DMSO group | GM1 group |
|---|---|---|---|---|---|
| Cerebrum | 0.23±0.02 | 0.47±0.01a,b | 0.36±0.02 | 0.48±0.02a,b | 0.36±0.02 |
| Cerebellum | 0.24±0.03 | 0.48±0.02a,b | 0.38±0.02 | 0.49±0.02a,b | 0.38±0.03 |
| Brainstem | 0.22±0.03 | 0.40±0.03a,b | 0.30±0.03 | 0.40±0.02a,b | 0.29±0.03 |
Data are presented as the mean ± standard error of the mean.
a
P<0.05 vs. the CK group
b
P<0.05 vs. the CU and GM1 groups. AQP4, aquaporin-4; SABC, streptavidin-biotin complex; OD, optical density; CK, control group; CU, curcumin-treated group; HH, hypoxia-hypercapnia group; DMSO, dimethyl sulfoxide solvent group; GM1, monosialoganglioside group.