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. 2016 Jan 22;11(3):978–984. doi: 10.3892/etm.2016.3018

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Copyright: © Zhu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — BBR treatment suppresses IR-induced cytokine expression in the serum. ELISA was employed to assess the expression of inflammatory cytokines in the serum. The expression levels of (A) TNF-α, (B) IL-1β and (C) IL-6 were determined after 4 h myocardial I/R insult. ***P<0.001, ^##P<0.01, ^###P<0.001. Ten rats were included in each study group. BBR, berberine; I/R, ischemia/reperfusion; IRI, I/R injury; TNF, tumor necrosis factor; Il, interleukin; ELISA, enzyme-linked immunosorbent assay.