Table II.

Adverse events.

	Discontinued participants, n		Mild to moderate adverse events, n/total n		Serious adverse events n/total n
First author, year (ref.)	Experimental	Control	Experimental	Control	Experimental	Control
Idan et al, 2010 (15)	19	14	13/55	5/55	8/55	11/55
Ho et al, 2012 (21)	4	2	3/60	1/60	1/60	1/60
Kaufman et al, 2011 (18)	66	12	134/234	15/40	5/234	1/40
Emmelot-Vonk et al, 2008 (7)	16	14	104/113	105/110	5/113	10/110
Srinivas-Shankar et al, 2010 (17)	15	16	10/130	7/132	6/130	3/132
Behre et al, 2012 (6)	15	24	12/183	10/179	7/183	6/179