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. 2016 Jan 21;4(3):313–324. doi: 10.3892/br.2016.577

Figure 1.

Figure 1.

Representative traces of epicardial monophasic action potential (MAP) recordings obtained during regular 8 Hz pacing. (A) A typical regular rhythm with each MAP occurring directly after its preceding stimulus can be observed under control conditions (5.2 mM [K+]). (B) Hypokalaemia (3 mM [K+]) produced both ventricular premature beats (VPBs) and (C) ventricular tachycardia (VT). (D) Heptanol at 0.1 mM prevented VT but did not affect VPBs, (E) whereas at 2 mM prevented VPBs and VT during hypokalaemic conditions. (F) The proportion of hearts showing VPBs was significantly increased by hypokalaemia (Fisher's exact test, *P<0.05). This was unaltered by heptanol at 0.1 mM (P>0.05), but subsequently decreased at 2 mM (†P<0.05). (G) The proportion of hearts showing VT was significantly increased by hypokalaemia (**P<0.01) and subsequently decreased by 0.1 and 2 mM heptanol (††P<0.01).