(A) Epicardial and (B) endocardial ventricular effective refractory periods (VERPs) obtained during programmed electrical stimulation. Significant differences from *normokalaemic and †hypokalaemic values, respectively. Epicardial and endocardial VERPs were significantly reduced by hypokalaemia (analysis of variance, **P<0.01 and ***P<0.001 for epicardium and endocardium, respectively), but restored to normokalaemic values by 0.1 mM heptanol (P>0.05). These were further increased by 2 mM heptanol (*P<0.05). (††P<0.01, †††P<0.001).