Figure 1.
Various phenotypes of invasive breast cancer cells according to the expression of ALDH1 and CD133. Invasive breast cancer cells were stained by SP immunohistochemical double staining. ALDH1-positive cells exhibited dark blue stained cytoplasm, while CD133-positive cells exhibited a red stained cell membrane. (A) ALDH1+/CD133+ phenotype. Magnification, ×200. (B) ALDH1+/CD133- phenotype. Magnification, ×100. (C) ALDH1-/CD133+ phenotype. Magnification, ×200. (D) ALDH1-/CD133- phenotype. Magnification, ×100. White arrows indicate the corresponding phenotype cells. ALDH, aldehyde dehydrogenase; CD, cluster of differentiation; SP, streptavidin-peroxidase.