Table II.
Correlation between VEGF expression and vessel-associated factors in ALDH1+/CD133+ stem-like cells in invasive ductal breast carcinoma.
| Vessel-associated factors | Positive (n=31) | Negative (n=89) | P-value |
|---|---|---|---|
| Positive percentage of VEGF, n (%) | 26 (83.9) | 56 (62.9)c | <0.05 (χ2 test) |
| MVD (CD34)a, mean ± SD | 28.78±10.55 | 25.90±8.34 | <0.05 (t test) |
| MVD (CD105)b, mean ± SD | 21.29±9.06 | 16.35±8.10 | <0.01 (t test) |
a
MVD was assessed by IHC using monoclonal antibody against CD34.
b
MVD was assessed by IHC using monoclonal antibody against CD105.
c
The VEGF-positive rate was 68.33% (82/120) among the 120 patients, thus 56 VEGF-positive patients did not possess ALDH1+/CD133+ stem-like cells in invasive ductal breast carcinoma. VEGF, vascular endothelial growth factor; MVD, microvessel density; ALDH, aldehyde dehydrogenase, CD, cluster of differentiation; IHC, immunohistochemistry; SD, standard deviation.