Table I.
Clinical and molecular characteristics at diagnosis in adult patients with B-cell acute lymphoblastic leukemia, according to LMO2 expression.
| Characteristic | Total, value | High LMO2 expression, value | Low LMO2 expression, value | P-value |
|---|---|---|---|---|
| Total, n (%) | 85 (100.0) | 46 (46.0) | 39 (39.0) | |
| Age, years | ||||
| Median | 52 | 50 | 52 | 0.64 |
| Range | 19–62 | 19–60 | 19–61 | |
| Gender, n (%) | ||||
| Male | 48 | 26 (56.5) | 22 (56.4) | 0.60 |
| Female | 37 | 20 (43.5) | 17 (43.6) | |
| TWBC, n (%) | ||||
| >50×109 cells/l | 34 | 18 (39.1) | 16 (41.0) | 0.32 |
| <50×109 cells/l | 51 | 29 (63.0) | 22 (56.4) | |
| Immunophenotype, n (%) | ||||
| Pro-B | 25 | 17 (37.0) | 6 (15.4) | 0.01 |
| Common (CD10+) | 51 | 27 (58.7) | 26 (66.6) | |
| Pre-B | 8 | 2 (4.3) | 6 (15.4) | |
| Mature | 1 | 0 (0.0) | 1 (2.6) |
LMO2, LIM domain only protein 2; TWBC, total white blood cell count; CD, cluster of differentiation.