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. 2016 Jan 20;11(3):1911–1916. doi: 10.3892/ol.2016.4132

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Figure 1. — Percentage of CD14⁺HLA-DR^low/− monocytes in circulating blood is increased in patients with RCC. (A) Representative FACS analysis of CD14⁺HLA-DR^low/− monocytes in the peripheral blood mononuclear cells of a healthy control donor and a patient with RCC. (B) The percentage of CD14⁺HLA-DR^low/− monocytes in circulating CD14⁺ monocytes of healthy donors and patients was analyzed. The difference between the groups was statistically analyzed using the Mann-Whitney U test. (C) The percentage of CD14⁺HLA-DR^low/− monocytes in blood samples of 4 RCC patients pre-surgery and post-surgery. Left panel: Representative FACS analysis of pt.4. Right panel: Quantification of all patients. CD, cluster of differentiation; HLA, human leukocyte antigen; RCC, renal cell carcinoma; HLA-DR^low/−, cells with a lower HLA-DR expression or are negative for HLA-DR; FSC, forward scatter; SSC, side scatter; PE, phycoerythrin; FITC, fluorescein isothiocyanate; Pt, patient; FACS, fluorescence-activated cell sorting.