Figure 1.

AZD5363 inhibits the proliferation of liver cancer cells. (A) The HepG2 and Huh7 cells were exposed to AZD5363 at varying concentrations (range, 5–30 µM). The cells were then cultured for 72 h, and the inhibitory rate was measured by a CCK-8 assay. Dose-dependent inhibition of each cell line was noted. (B) Concentrations of IC₅₀ that the two cell lines were exposed to for the different time periods of AZD5363 exposure. IC₅₀, half maximal inhibitory concentration; CCK-8, cell counting kit 8.