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. 2016 Jan 14;11(3):1685–1692. doi: 10.3892/ol.2016.4111

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — AZD5363 activates the phosphorylation of mTOR dependent of liver cancer cell type. AZD5363 activated the phosphorylation of mTOR in (A) the Huh-7 cells in a dose-dependent manner, but this was not observed in (B) the Hep-G2 cells. The expression levels in the (C) Huh-7 and (D) Hep-G2 cells were quantified using a gel imaging scan. The values are reported as the mean ± standard error of the mean. **P<0.01. mTOR, mammalian target of rapamycin; pmTOR, phosphorylated mTOR; GAPDH, glyceraldehyde 3-phosphate dehydrogenase.