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Association between the expression of topoisomerase IIα and the pathological complete response rate.
| Pathological complete response rate | |||||
|---|---|---|---|---|---|
| Topoisomerase IIα expression | Overall | HR−/HER2− | Any HR/HER2+ | HR+/HER2− | P-value |
| Positive | 19/88 (22%) | 8/19 (42%) | 6/5 (40%) | 5/54 (9%) | 0.051 |
| Negative | 7/59 (12%) | 2/6 (33%) | 2/5 (40%) | 3/48 (6%) | 0.019 |
HR, hormone receptor; HER2, human epidermal growth factor receptor 2.
