Figure 1.

(A) The mRNA level of PREX2 was examined in HCC tissues and Normal tissue using reverse transcription-quantitative polymerase chain reaction. (B) The mRNA and (C) protein level of PREX2 was determined using western blot analysis in various HCC cell lines. The human normal liver THLE-3 cell line was used as a control. **P<0.01 vs. control. mRNA, messenger RNA; PREX2, phosphatidylinositol-3,4,5-trisphosphate Rac exchanger 2; HCC, hepatocellular carcinoma; Normal, matched adjacent normal tissue.