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Protein expression of DNMT1 (Substrate P, ×400 magnification; hematoxylin and eosin stained). Negative expression of DNMT1 protein in (A) normal breast specimen and (B) ERα-positive breast cancer specimen. (C) Positive expression of DNMT1 protein in ERα-negative breast cancer specimen. ER, estrogen receptor; DNMT, DNA methyltransferase. All images are representative.
