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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Am J Obstet Gynecol. 2015 Oct;213(4 0):S29–S52. doi: 10.1016/j.ajog.2015.08.040

Figure 3.

Figure 3

Migration of the neutrophils from decidual vessels into the chorioamniotic membranes. (A) Normal histology of the chorioamniotic membranes, which are composed of amnion and chorion laeve. The decidua is adjacent to the chorion and contains maternal capillaries (black asterisk). Neutrophils migrate from the maternal circulation in the presence of chemotactic gradient (increased amniotic fluid neutrophil chemokine concentrations). (B) Progression of neutrophils from the decidual vessels (in red) towards the amnion. The location of bacteria is within the amniotic cavity. Initially, neutrophils accumulate in the choriodecidual interface (B; left); however, in subsequent stages, invade the chorion (B, center) and amnion (B, right).