Table-1.

Effect of ethanolic extract of seeds of H. antidysenterica on castor oil induced diarrhea in rats.

Group (n=5)	Treatment	Total no. of wet dropping/cage in 4 h	Average no of wet dropping/animal in 4 h	% Inhibition of defecation
Group A-I	Saline at 20 ml/kg body wt.	0.00±0.00a	0.00±0.00a	0.00±0.00a
Group A-II	Saline at 20 ml/kg body wt.+1 ml castor oil	35.00±0.58d	7.00±0.12d	0.00±0.00a
Group A-III	Loperamide at 5 mg/kg body wt.+1 ml castor oil	15.00±0.58b	3.00±0.12b	57.17±0.94c
Group A-IV	HAE at 100 mg/kg body wt.+1 ml castor oil	25.00±0.58c	5.00±0.12c	28.47±2.83b
Group A-V	HAE at 200 mg/kg body wt.+1 ml castor oil	16.67±0.88b	3.33±0.17b	52.27±3.28c
Group A-VI	HAE at 400 mg/kg body wt.+1 ml castor oil	16.33±0.33b	3.26±0.06b	54.18±1.37c

Values are expressed as mean±SEM (n=5), and bearing different superscript was considered significant (p<0.05) when compared with control groups. HAE=Ethanolic extract of Holarrhena antidysenterica seed, SEM=Standard error of the mean, H. antidysenterica=Holarrhena antidysenterica