Skip to main content
. Author manuscript; available in PMC: 2016 Mar 2.
Published in final edited form as: J Infect Dis. 2009 Aug 1;200(3):453–463. doi: 10.1086/600073

Figure 2.

Figure 2

Three-step method for calculating regimen-specific genotypic susceptibility scores (GSSs): (1) calculate drug-specific GSSs, applying a genotypic drug-resistance interpretation algorithm to the mutations present in the baseline genotype to estimate the activity of an antiretroviral (ARV) relative to its activity against a wild-type virus; (2) calculate the weighted drug-specific GSSs, multiplying drug-specific GSSs by a factor that accounts for differences in ARV activity between ARVs belonging to different ARV classes; and (3) calculate regimen-specific GSSs by adding the weighted drug-specific GSSs of the drugs used for salvage therapy.