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. Author manuscript; available in PMC: 2016 Mar 2.
Published in final edited form as: J Infect Dis. 2009 Aug 1;200(3):453–463. doi: 10.1086/600073

Figure 4.

Figure 4

Classification tree for the comprehensively weighted version of regimen-specific genotypic susceptibility scores (rGSSs) generated by the HIVdb algorithm. The root node contains all 734 treatment-change episodes (TCEs). The root node and all child nodes show the number of TCEs resulting in virologic failure (left side of node) or virologic success (right side of node). Using the R package Rpart (Recursive partitioning; version 3.1-39), an explanatory variable and a cutoff value were selected at each node to optimally separate virologic responders from nonresponders in the child nodes. Tree pruning was performed using the default parameters in Rpart for minimizing the complexity of the tree as a function of the improvement in classification accuracy. ARV, antiretroviral; HIV, human immunodeficiency virus.