Table 2. Summary of biochemical screens of P. falciparum protein kinases.
Target | median Z’ | # of initial hits (hit rate) | # of confirmed sub-μM hits |
---|---|---|---|
CDPK1 | 0.71 | 220 (1.6%) | 181 |
CDPK4 | 0.84 | 77 (0.6%) | 56 |
MAPK2 | 0.66 | 0 (0%) | 0 |
PK6 | 0.34 | 83 (0.6%) | 65 |
PK7 | 0.48 | 2 (0.01%) | 2 |