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. 2016 Mar 2;11(3):e0149996. doi: 10.1371/journal.pone.0149996

Table 3. Summary of kinobead competition assays (results reflect two independent experiments).

Compound Inhibition of HepG2 cell growth at 10 μM [3] Human kinases quantified on kinobeads (N = 2) Human kinases with apparent pKd ≥ 4.7 (N = 2) Human kinases with apparent pKd ≥ 6 (N = 2)
TCMDC-125885 33% 153 5 1
TCMDC-134116 43% 136 126 96
TCMDC-141154 48% 146 47 26
TCMDC-141399 47% 147 63 24