Table E2.
Crude associations between maternal geohelminth infections and study outcomes
| Geohelminth variable | Eczema to 3 y |
Wheeze to 3 y |
Allergen SPT reactivity at 3 y |
SPT reactivity to HDM at 3 y |
||||
|---|---|---|---|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |
| Any maternal geohelminth presence | ||||||||
| No (54.1%) | 1 | 1 | 1 | 1 | ||||
| Yes (45.9%) | 1.31 (1.05-1.65) | .018 | 1.17 (0.96-1.43) | .110 | 0.84 (0.66-1.05) | .131 | 0.66 (0.48-0.91) | .010 |
| Maternal A lumbricoides presence | ||||||||
| No (72.5%) | 1 | 1 | 1 | 1 | ||||
| Yes (27.5) | 1.44 (1.13-1.84) | .003 | 1.38 (1.11-1.72) | .003 | 0.74 (0.57-0.97) | .031 | 0.51 (0.34-0.77) | .001 |
| Intensity | ||||||||
| Uninfected (77.8%) | 1 | 1 | 1 | 1 | ||||
| Light (17.1%) | 1.28 (0.92-1.78) | .150 | 1.33 (1.03-1.72) | .027 | 0.68 (0.49-0.96) | .030 | 0.51 (0.31-0.84) | .008 |
| Moderate/heavy (5.1%) | 1.45 (0.85-2.50) | .176 | 1.63 (1.07-2.48) | .022 | 0.88 (0.52-1.51) | .647 | 0.46 (0.18-1.15) | .095 |
| Maternal T trichiura presence | ||||||||
| No (71.1%) | 1 | 1 | 1 | 1 | ||||
| Yes (28.9%) | 1.21 (0.92-1.60) | .181 | 1.16 (0.93-1.43) | .181 | 0.85 (0.66-1.10) | .222 | 0.65 (0.45-0.94) | .022 |
| Intensity | ||||||||
| Uninfected (73.8%) | 1 | 1 | 1 | 1 | ||||
| Light (22.0%) | 1.20 (0.88-1.64) | .243 | 1.20 (0.88-1.64) | .854 | 0.83 (0.62-1.11) | .209 | 0.66 (0.44-1.00) | .053 |
| Moderate/heavy (4.2%) | 1.75 (0.99-3.58) | .053 | 1.75 (0.99-3.09) | .576 | 0.67 (0.36-1.31) | .254 | 0.22 (0.05-0.92) | .037 |
| Maternal hookworm presence | ||||||||
| No (94.4%) | 1 | 1 | 1 | 1 | ||||
| Yes (5.6%) | 1.51 (0.92-2.49) | .106 | 0.87 (0.56-1.36) | .541 | 0.79 (0.46-1.35) | .384 | 0.79 (0.38-1.65) | .535 |
ORs and 95% CIs were estimated using logistic regression. P values of less than .05 are shown in boldface. Uninfected data for prevalence are derived from the results of all parasitologic methods, whereas those for infection intensity form Kato-Katz results.