Table 2. Factors associated with CD4 change after six months of ART.
| No. | Mean change±sd | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|---|
| difference | p | difference | p | 95%CI | |||
| Total | 4795 | 122.4±114.8 | |||||
| HBsAg testing | |||||||
| Negative | 3365 | 121.8±109.8 | |||||
| Positive | 414 | 109.9±102.8 | -11.90 | 0.05 | -10.17 | 0.08 | (-21.56, 1.22) |
| Not tested | 1016 | 129.6±133.8 | 7.84 | 0.06 | 9.29 | 0.10 | (-1.77, 20.35) |
| HCV antibody testing | |||||||
| Negative | 3010 | 124.6±109.8 | |||||
| Positive | 512 | 90.3±93.8 | -34.27 | <0.001 | -23.91 | <0.001 | (-36.52, -11.30) |
| Not tested | 1273 | 130.0±131.0 | 5.43 | 0.16 | 3.83 | 0.47 | (-6.48, 14.13) |
| Sex | |||||||
| Male | 3329 | 122.3±115.3 | |||||
| Female | 1463 | 122.8±113.6 | 0.50 | 0.89 | -0.42 | 0.91 | (-7.91, 7.06) |
| Change | 3 | 0±152.0 | -122.32 | 0.07 | -125.77 | 0.05 | (-251.88, 0.34) |
| Age (years) | |||||||
| ≦30 | 1134 | 126.2±117.3 | |||||
| 31–50 | 3179 | 122.3±114.5 | -3.88 | 0.33 | -6.12 | 0.12 | (-13.80, 1.55) |
| >50 | 482 | 114.3±111.0 | -11.87 | 0.06 | -17.88 | 0.004 | (-30.01, -5.74) |
| Mode of infection | |||||||
| Heterosexual contact | 3306 | 123.6±112.6 | |||||
| Homosexual contact | 794 | 131.5±122.9 | 7.91 | 0.08 | 7.34 | 0.15 | (-2.65, 17.33) |
| Injecting drug use | 316 | 82.7±100.7 | -38.94 | <0.001 | -22.11 | 0.005 | (-37.59, -6.63) |
| Blood products | 40 | 119.7±139.3 | -3.87 | 0.83 | 3.70 | 0.84 | (-31.33, 38.73) |
| Other | 339 | 124.8±120.1 | 1.15 | 0.86 | -0.83 | 0.90 | (-13.60, 11.94) |
| Baseline CD4 count | |||||||
| ≦50 | 1484 | 114.0±74.6 | |||||
| 51–200 | 1921 | 132.7±115.8 | 18.68 | <0.001 | 20.08 | <0.001 | (12.21, 27.94) |
| 201–350 | 1113 | 132.8±127.4 | 18.80 | <0.001 | 22.23 | <0.001 | (12.58, 31.88) |
| 351–500 | 188 | 84.2±166.1 | -29.82 | 0.001 | -26.36 | 0.004 | (-44.17, -8.55) |
| ≧501 | 89 | -7.8±208.2 | -121.79 | <0.001 | -113.42 | <0.001 | (-138.21, -88.63) |
| Baseline HIV viral load | |||||||
| 40–20,000 | 669 | 86.7±180.2 | |||||
| 20,001–80,000 | 618 | 121.4±107.6 | 34.72 | <0.001 | 23.11 | <0.001 | (10.73, 35.49) |
| 80,001–200,000 | 570 | 131.7±109.4 | 44.97 | <0.001 | 35.11 | <0.001 | (22.31, 47.91) |
| >200,000 | 795 | 148.2±132.6 | 61.51 | <0.001 | 47.94 | <0.001 | (36.04, 59.84) |
| Not tested | 2145 | 120.7±110.6 | 34.00 | <0.001 | 28.04 | <0.001 | (17.57, 38.50) |
| CDC stage | |||||||
| CDC A | 2433 | 121.6±120.0 | |||||
| CDC B | 524 | 116.2±104.3 | -5.43 | 0.33 | -7.28 | 0.19 | (-18.06, 3.50) |
| CDC C | 1838 | 125.2±110.6 | 3.56 | 0.32 | 4.25 | 0.27 | (-3.31, 11.81) |
| HIV-1 subtype | |||||||
| B | 144 | 144.1±132.4 | |||||
| 01AE | 78 | 111.6±76.7 | -32.4 | 0.04 | -35.47 | 0.03 | (-66.69, -4.25) |
| 07BC | 2 | 188.5±46.0 | 44.45 | 0.59 | 33.44 | 0.67 | (-121.84, 188.72) |
| C | 4 | -30.0±233.9 | -174.05 | 0.003 | -169.64 | 0.003 | (-280.27, -59.02) |
| Not tested | 4567 | 122.0±114.6 | -22.05 | 0.02 | -20.52 | 0.04 | (-39.72, -1.33) |