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. 2016 Mar 2;11(3):e0148562. doi: 10.1371/journal.pone.0148562

Table 3. Defense response genes induced in udder in vivo by E. coli.

Symbol Name Function
BCL2 B-cell CLL/lymphoma 2 Transcription
BNBD-9-LIKE BNBD-9-LIKE Bactericidal activity
C1S complement component 1, s Peptidase
C3 complement component 3 Complement activation
C4BPA complement component 4 bp, alpha Complement activation
C6 complement component 6 Lytic complex formation
CCL20 chemokine (C-C motif) ligand 20 Chemotactic factor
CCL3 chemokine (C-C motif) ligand 3 inflammation and chemokine
CCL4 chemokine (C-C motif) ligand 4 inflammation and chemokine
CCL5 chemokine (C-C motif) ligand 5 Chemotactic factor
CCR5 chemokine (C-C motif) receptor 5 Chemokine Receptor
CD14 CD14 molecule Mediates response to LPS
CFB complement factor B Complement component cleavage
COTL1 coactosin-like 1 (Dictyostelium) Binding to F-actin
CXCL11 chemokine (C-X-C motif) ligand 11 Chemotactic factor
CXCL16 chemokine (C-X-C motif) ligand 16 Chemotactic response
CYBA cytochrome b-245 alpha Critical in Phagocyte oxidation
DEFB10 beta-defensin 10 Bactericidal activity
DEFB4A beta-defensin 4 Bactericidal activity
FCER1G Fc fragment of IgE Immune response regulation
FGR Gardner-Rasheed feline Catalysis
FN1 fibronectin 1 Cell surface and compounds binding
HMOX1 heme oxygenase (decycling) 1 catalysis
IL1A interleukin 1, alpha Stimulate thymocyte proliferation
IL1B interleukin 1, beta Stimulate thymocyte proliferation
ITGB6 integrin, beta 6 Receptor for fibronectin and cytoactin
LAP lingual antimicrobial peptide Antibacterial and antifungal activities
LBP lipopolysaccharide binding protein Bactericidal activity
LOC504773 regakine 1 Immunoattractant
LTF lactotransferrin catalytic activity
LYZ2 lysozyme C-2 catalytic activity
NCF1 neutrophil cytosolic factor 1 NADPH activation
NFKBIZ NF kappa B-cells inhibitor zeta NFkB signaling
NOS2 nitric oxide synthase 2 catalytic activity
OLR1 oxidized LDL receptor 1 Involved in degradation of oLDL
ORM1 alpha-1 acid glycoprotein Modulate immune system activity
PTAFR platelet-activating factor receptor inflammation
PYCARD PYD and CARD domain containing Promotes caspase-mediated apoptosis
RAB27A member RAS oncogene family GTPase superfamily
S100A12 S100 calcium binding protein A12 Belongs to the S-100 family
SAA3 serum amyloid A3 Major acute phase reactant
SELP selectin P Receptor for myeloid cells
SERPINF2 serpin peptidase inhibitor Plasmin, trypsin, chymotrypsin inhibitor
THBS1 thrombospondin 1 Cell to cell or matrix interaction mediator
TLR2 toll-like receptor 2 Mediates response to LPS
VNN1 vanin 1 catalytic activity