Table 8. Clusters of ontological categories suppressed or induced by LPS.
| Table 8: Ontological Categories in PMECs Challenged with Lipopolysaccharide | |||||
|---|---|---|---|---|---|
| INDUCED | SUPRESSED | ||||
| Ontological categories | p Value | Ontological categories | p Value | ||
| 1 | 2.59 | 1 | 1.52 | ||
| # | immune response | 2.78E-08 | # | extracellular region | 1.31E-02 |
| positive regulation of immune system process | 5.27E-03 | extracellular region part | 1.91E-02 | ||
| 2 | 2.55 | 2 | 1.48 | ||
| # | Antigen processing and presentation | 3.05E-05 | calcium ion binding | 8.55E-03 | |
| peptide or polysaccharide antigen via MHC class II | 3.62E-03 | metal ion binding | 4.75E-02 | ||
| 3 | 2.35 | ||||
| # | defense response | 2.19E-06 | |||
| immune effector process | 3.29E-05 | ||||
| 4 | 2.02 | ||||
| # | extracellular region | 1.63E-03 | |||
| inflammatory response | 2.24E-03 | ||||
| 5 | 1.83 | ||||
| # | positive regulation of endocytosis | 2.10E-03 | |||
| regulation of vesicle-mediated transport | 1.83E-02 | ||||
| 6 | 1.56 | ||||
| ISG15-protein conjugation | 5.72E-07 | ||||
| proteolysis | 1.52E-02 | ||||
| 7 | 1.25 | ||||
| serine-type peptidase activity | 2.61E-02 | ||||
| peptidase activity, acting on L-amino acid peptides | 4.39E-02 | ||||
| 8 | 1.03 | ||||
| apoptosis | 7.89E-02 | ||||
| programmed cell death | 8.28E-02 | ||||
Only clusters with enrichment scores better than 1.0 are given. Note the significantly higher p-values due to a smaller set of microarrays analyzed. The subset of clusters regulated similarly by E. coli is marked with # signs.