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. Author manuscript; available in PMC: 2016 Mar 2.
Published in final edited form as: Kidney Int. 2010 Oct 20;79(4):404–413. doi: 10.1038/ki.2010.398

Figure 2. Increased podocyte apoptosis in female αERKO mice.

Figure 2

Podocyte apoptosis in female wild-type (WT) littermates (a) and female αERKO mice (b), as detected by TUNEL assay. Yellow arrows indicate TUNEL-positive cells, whereas the red arrow indicates an artifactual staining of a red blood cell. Results are expressed as percentage of number of TUNEL-positive cells on the total number of glomerular cells and graphed as the mean ± s.e.m. (c). N = 5 mice/group. Original magnifications: × 400. Student’s t-test was performed.

(d) Representative images of caspase 3 immunofluorescence staining and colocalization with synaptopodin expression, used as podocyte marker, in female WT littermates and female αERKO mice. TUNEL, terminal dUTP nick-end labeling.