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. Author manuscript; available in PMC: 2016 Mar 2.
Published in final edited form as: Kidney Int. 2010 Oct 20;79(4):404–413. doi: 10.1038/ki.2010.398

Figure 6. T induces in vitro podocyte apoptosis.

Figure 6

Podocytes were treated in vitro with vehicle (V), T (1 nmol/l), E2 (1 nmol/l), flutamide (100 nmol/l), ICI 182780 (ICI, 1 µmol/l), or a combination. Apoptosis was measured in terms of TUNEL-positive cells (%) (see Materials and Methods for details). Data are the mean ± s.e.m. of 3–5 independent experiments. ANOVA with Newman-Keuls’ multicomparison test was performed. *P < 0.001 compared with vehicle alone, #P < 0.001 compared with T alone, $P < 0.001 compared with E2 + T. ANOVA, analysis of variance; E2, 17β-estradiol; 17α-E2, 17α-estradiol; T, testosterone; TUNEL, terminal dUTP nick-end labeling.