Figure 10.

Scheme and coexpression network for a putative flavonol synthesis pathway in tobacco flowers. A, Outline of a potential flavonoid synthesis pathway for tobacco (based on metabolites measured in Fig. 7 and Supplemental Fig. S6). CHS, Chalcone synthase; CHI, chalcone isomerase; F3H, flavanone 3-hydroxylase; FLS, flavonol synthase; FGT, flavonol glycosyl transferase. B, Coexpression network of EB427179 (large node) corresponding to tobacco methyltransferase_2 module 177 (Fig. 8). Nodes depict genes (probe set identifiers are associated with nodes), and edges depict coexpression relationships as outlined by Mutwil et al. (2011). Colored shapes of the nodes indicate the label co-occurrence that the respective gene is associated with. Genes that correspond to enzymes in the flavonoid pathway scheme (A) are highlighted in boldface and are associated with respective boxes. The grayed-out, transparent part of the network represents nodes that are not supported by the ELA.