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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Cancer Res. 2015 Dec 30;76(5):1066–1077. doi: 10.1158/0008-5472.CAN-15-0391

Fig. 6.

Fig. 6

Combination therapy inhibits tumor growth. (A) Combination PDT and L-IRI enhanced MIA PaCa-2 tumor volume reduction, determined by longitudinal ultrasound imaging. (B) Representative snapshots of MIA PaCa-2 tumors 3-weeks post-treatment. Scale bar=2cm. Tumor weights at this time showed the combination inhibited tumor growth. (C) Fold change in tumor volume 2-weeks post-treatment shows significantly lower volume in the combination group. (D) Combination PDT and L-IRI also enhanced AsPC-1 tumor volume reduction. (E) Representative snapshots of AsPC-1 tumors 3-weeks post-treatment. Scale bar, 2cm. Tumor weights at this time showed the combination slowed tumor growth. (F) A sustained and prolonged MIA PaCa-2 tumor growth inhibition was observed after two cycles of combination administered on 9 and 27 days post-implantation. Arrow indicates day of treatment. (*P<0.05,**P<0.01,***P<0.001, Kruskal–Wallis One-way ANOVA) (N=8–18)