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. Author manuscript; available in PMC: 2016 Mar 9.
Published in final edited form as: Cell Rep. 2016 Feb 18;14(8):1901–1915. doi: 10.1016/j.celrep.2016.01.067

Figure 1. Combinatorial Hox Profiles Define Forelimb Innervating MNs.

Figure 1

(A) Schematic of the primary motor nerves supplying the mouse forelimb at e12.5. Dorso-ventral (D–V), medio-lateral (M–L) and proximo-distal (Pr-Di) axes are indicated. (B) Topographical organization of forelimb MNs. MN positions are based on retrograde labeling from nerves at e12.5 (see Figure S1A–I). Dorso-ventral (D–V) and medio-lateral (M–L) coordinates are indicated. Segmental position of labeled LMC neurons are indicated, and extend from cervical segment 4 (C4) to thoracic segment 1 (T1). Non-LMC MN populations present in these segments are also outlined. (C–G) Hoxc4, Hoxa5, Hoxc5, Hoxc6 and Hoxc8 expression in retrogradely labeled MNs projecting along the suprascapular, lateral pectoral, musculocutaneous, axillary, thoracodorsal, medial anterior lateral, radial, median and ulnar nerves. (H) Summary of Hox expression profiles in MNs projecting along the main forelimb motor nerves. See also Figure S1.