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Animal Experimental Design
| Monovalent Guinea Pig Studies | ||
|---|---|---|
| Group # | n | Total Antigen per Vaccination(µg)* |
| 1 | 4 | 100 |
| 2 | 4 | 50 |
| 3 | 4 | 15 |
| 4 | 4 | 5 |
| 5 | 4 | 1 |
| 6 | 4 | 0.1 |
| 7 | 4 | 0 |
Animals were immunized with a total of 20 mg of powder via both nares. Each nare received 10 mg of powder or half of the total antigen dose.
