Skip to main content
. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Cancer Res. 2016 Feb 2;76(5):1204–1213. doi: 10.1158/0008-5472.CAN-15-2265

Figure 1. G0s2 null cells have an increased susceptibility to undergo oncogene induced transformation.

Figure 1

A, Wild-type (WT-E2, WT-E10) and G0s2 null (G0S2−/− E4, G0S2−/− E6) immortalized MEFs were transfected with either an insertless control vector or an HRAS (V12) expression plasmid. Cells were stained 14 days after transfection with Giemsa. Left are representative plates. Right is the average of two biological replicates where error bars indicate the range in values. The experiment was repeated four times with similar results. B, WT-E10 and G0S2 −/− E6 cells were transfected with either an insertless control vector or an EGFR expression plasmid. Cells were stained 14 days after transfection with Giemsa. Left are representative plates. Right is the average of two biological replicates where error bars indicate the range in values. The experiment was repeated two times with similar results. C, G0S2 −/− E6 cells were transfected with an HRAS (V12) expression plasmid and either an insertless control vector or G0S2 expression plasmid. Cells were stained 14 days after transfection with Giemsa. Left are representative plates. Right is the average of biological triplicate determinations and error bars are standard deviation. ** = P < 0.01. The experiment was repeated three times with similar results.