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. Author manuscript; available in PMC: 2017 Feb 8.
Published in final edited form as: Neurochem Res. 2016 Feb 8;41(0):398–408. doi: 10.1007/s11064-016-1838-8

Fig 3.

Fig 3

Effect of D-serine (1 mM) on NMDA (300 μM)-induced [3H]dopamine release from mouse striatal tissue (Top Panel). D-Serine was added to the perfusion buffer at fraction 1 and maintained throughout the collection period. NMDA was added at fraction 5 for one fraction. NMDA induced [3H]dopamine release (■), but D-serine did not affect the release (□). Values are expressed as mean fractional release ± S.E., n =6. Mice were treated with CBIO (30 mg/kg) and killed one hour later and striatal tissue incubated as above (Bottom Panel). NMDA-induced [3H]dopamine was measured (bottom). NMDA + D-serine induced [3H]dopamine release (▲), but prior CBIO treatment (△) did not affect the fractional release. Values are expressed as mean fractional release ± S.E., n = 6.