Figure 6. Fenofibrate and tesaglitazar reduce duration of ethanol-induced loss of righting reflex in B6 and B6 × 129S4 mice.
A. Duration of LORR (min) in B6 males (n=5–6 per group). B. BEC (mg/dl) at regaining of righting reflex (RORR) in B6 males. C. Duration of LORR (min) in B6 × 129S4 males (n=5–12 per group). D. Duration of LORR (min) in B6 females (n=5–6 per group). The ethanol dose was 3.6 g/kg. Data were analyzed by one-way ANOVA followed by Bonferroni’s test [***p<0.001 compared to control; ###p<0.001 comparison between fenofibrate (Feno) and tesaglitazar (Tesa)].