Fig. 2.
Combination of GCS-100 and ABT-737 potently reduces AML cells. OCI-AML3 and THP-1 cells were treated with vehicle (0.1% DMSO) or GCS-100 (125 µg/ml or 250 µg/ml) +/− ABT-737 for 48 h. Total viable cells (Ann V −/ DAPI – with bead count; OCI-AML3 in “A” and THP-1 in “B”) were determined by FACSCAN analysis. * represents p < 0.05; ** represents p < 0.01, *** represents p < 0.001 as determined by Student t test.