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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Biochim Biophys Acta. 2015 Dec 17;1863(4):562–571. doi: 10.1016/j.bbamcr.2015.12.008

Fig. 7.

Fig. 7

Suppression of p53 protects AML cells from GCS-100/ ABT-737 combination. OCI-AML3 transductant cells with either LKO vector control shRNA or p53 shRNA were treated with vehicle (0.1% DMSO) or GCS-100 (125 µg/ml or 250 µg/ml) or 1 µM ABT-737 for 48 h. Ratio of total viable cells (Ann V −/ DAPI – with bead count; “A”) relative to the average of viable cells treated with DMSO and percentage of apoptotic cells (Ann V +; “B”) was determined by FACSCAN analysis. * represents p < 0.05; ** represents p < 0.01, *** represents p < 0.001 as determined by Student t test.