Table 1.
Chemokines recruiting monocytes, neutrophils and MDSC to the tumor
Chemokine | Cancer | Leukocyte infiltrate | Citation |
---|---|---|---|
CCL2 (MCP-1) | Prostate carcinoma | Monocytes/TAM | [99] |
Anaplastic thyroid carcinoma |
Monocytes/TAM | [100] | |
Breast, gastric, ovarian cancer |
MDSC | [32] | |
Colorectal cancer | MDSC | [25] | |
CCL5 (RANTES) | Breast carcinoma | Monocytes | [101, 102] |
CXCL5 | Mammary carcinoma (mouse) |
MDSC | [103] |
Non small cell lung cancer | PMN | [104] | |
Melanoma (mouse) | PMN-MDSC | [105] | |
CXCL6 (GCP-2) | Gastrointestinal tumors | PMN | [106] |
Tongue squamous cell carcinoma |
PMN | [107] | |
CXCL8 (IL-8) | Head and neck squamous cell carcinoma |
PMN | [107, 108] |
Gastric carcinoma | PMN | [109] | |
Bronchioalveolar carcinoma | PMN | [110] | |
Tongue squamous cell carcinoma |
PMN | [107] | |
CCL15 (MIP-5) | Colorectal cancer | PMN-MDSC | [103] |
CXCL12 (SDF-1) | Colorectal cancer | M-MDSC | [111] |
Mammary carcinoma (mouse) |
MDSC | [26] |
MDSC – total population of MDSC without defining specific subset