Table 3.

Cox models for incident metabolic syndrome by regional fat depot quantity and radiodensity. Both Model 1 and Model 2 were adjusted for age, gender, race, weight*, cigarette smoking*, exercise*, waist circumference*, triglycerides*, HDL*, SBP*, DBP*, glucose* (where * signifies time-varying covariates). Model 2 includes both regional fat quantity and radiodensity in the model to test whether radiodensity and quantity were independently associated with incident metabolic syndrome.

			Model 1		Model 2
Variable	Unadjusted HR	P-value	Adjusted HR	P-Value	Adjusted HR	P-Value
Visceral Fat Quantity	1.30 [1.23–1.38]	<0.0001	1.28 [1.17–1.39]	<0.0001	1.30 [1.16–1.46]	<0.0001
Visceral Fat Radiodensity	0.91 [0.89–0.93]	<0.0001	0.95 [0.93–0.98]	0.002	1.01 [0.97–1.05]	0.62
Subcutaneous Fat Quantity	1.16 [1.12–1.20]	<0.0001	1.06 [1.00–1.14]	0.06	1.05 [0.99–1.13]	0.12
Subcutaneous Fat Radiodensity	0.91 [0.89–0.94]	<0.0001	0.97 [0.93–1.00]	0.06	0.97 [0.94–1.01]	0.12
Intermuscular Fat Quantity	3.59 [2.39–5.41]	<0.0001	1.78 [0.96–3.31]	0.07	1.87 [0.90–3.89]	0.09
Intermuscular Fat Radiodensity	0.92 [0.88–0.95]	<0.0001	0.98 [0.94–1.03]	0.43	1.01 [0.95–1.07]	0.81

Abbreviations: HR, hazard ratio; CI, confidence interval.