Fig. 16.
(a) DOX release from SAD–PEG–SA and CAD–PEG–CAD at pH 5.5, 6.8 and 7.4 at 37 °C, (b) cytotoxic effects and (c) tumor volume evaluation, for free DOX, SAD–PEG–SA and CAD–PEG–CAD, (d) dendronized heparin–DOX based NPs with hydrazone bonds. (a–c reproduced from ref. 313. Copyright 2013 with permission from “John Wiley & Sons, Inc.”, and reproduced from ref. 308. Copyright 2013 with permission from “Elsevier”).