Table 3.
Virus | Guinea pigs | Rabbits | |
---|---|---|---|
Mayinga (wild-type) | 8mc, guinea pig-adapted | Mayinga (wild-type) | |
TNF activity, serum (U/mL) | 3.4 ± 0.1 (day 7) | 2.5 ± 0.16 (day 7) | 104 ± 36 (day 3) |
471 ± 137 (day 5) | |||
1398 ± 909 (day 9) | |||
| |||
Virus titer, serum (PFU) | 103 | 104–105 | Nondetectable |
| |||
TNF activity, peritoneal (U/mL) | Nondetectable | Nondetectable | 15.3 ± 2.1 (days 5–9) |
| |||
Virus titer, peritoneal (PFU) | 102–103 | 102–103 | Nondetectable |