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Affinity and intrinsic activity of Y-QA31 for dopamine receptors. (A) Competitive binding curves of Y-QA31 to dopamine receptor subtypes determined from radioligand-receptor binding assays. Data are representative of three to five independent experiments. (B and C) Antagonism of Y-QA31 for dopamine D3 and D2 receptors in [35S]GTPγS-binding assays. The data are representative of three independent experiments.
