Table 2. IC50 values of Y-QA31 for GPCRs.
| Receptor | IC50 | Receptor | IC50 | Receptor | IC50 |
|---|---|---|---|---|---|
| D1 | >10.0 μmol/L | 5-HT6 | >10.0 μmol/L | μ | >10.0 μmol/L |
| D2 | 220.2±48.4 nmol/L | 5-HT7 | 1.65±1.52 μmol/L | δ | >10.0 μmol/L |
| D3 | 1.74±0.47 nmol/L | α1A | 46.3±10.4 nmol/L | κ | >10.0 μmol/L |
| D4 | 877.3±150.1 μmol/L | α1B | 170.8±62.5 nmol/L | A1 | >10.0 μmol/L |
| D5 | >10.0 μmol/L | α2 | 2.17±2.38 μmol/L | A2A | >10.0 μmol/L |
| 5-HT1A | 11.70±3.87 nmol/L | β1 | >10.0 μmol/L | H1 | 568.5±95.7 nmol/L |
| 5-HT1B | 7.52±6.16 μmol/L | M1 | >10.0 μmol/L | H2 | >10.0 μmol/L |
| 5-HT1D | 677.9±254.1 nmol/L | M2 | >10.0 μmol/L | H3 | >10.0 μmol/L |
| 5-HT2A | 2.40±4.77 μmol/L | M3 | >10.0 μmol/L | CB1 | >10.0 μmol/L |
| 5-HT2C | 839.0±472.2 nmol/L | M4 | >10.0 μmol/L | CB2 | >10.0 μmol/L |
| 5-HT5A | 1.68±0.32 μmol/L | M5 | >10.0 μmol/L |