Table 3. Induction of catalepsy in mice by Y-QA31, clozapine, or haloperidol.
Drug | Dose (mg/kg) | n | Catalepsy (n) |
---|---|---|---|
Control | 10 | 0 | |
Y-QA31 | 40 | 10 | 0 |
80 | 10 | 3 | |
120 | 15 | 7b | |
160 | 10 | 7c | |
240 | 10 | 10c | |
320 | 10 | 10c | |
Drug | Dose (mg/kg) | n | Catalepsy (n) |
Control | 5 | 0 | |
Clozapine | 2.5 | 5 | 0 |
5 | 5 | 0 | |
7.5 | 10 | 7c | |
10 | 10 | 8c | |
20 | 10 | 7c | |
40 | 5 | 5c | |
80 | 5 | 5c | |
Drug | Dose (mg/kg) | n | Catalepsy (n) |
Control | 10 | 0 | |
Haloperidol | 0.16 | 10 | 0 |
0.32 | 10 | 3 | |
0.64 | 10 | 8c | |
1.28 | 10 | 10c | |
2.56 | 10 | 10c |
n=5–15 per value.
bP<0.05,
cP<0.01 vs control; Fisher's exact test.