Figure 8.

In the cultured H9C2 cells subjected to the SIR treatment, BBR effectively reduced the oxidative stress, whereas the JAK2 siRNA blocked this effect. The cells were exposed to the SIR treatment with or without BBR or JAK2 siRNA treatment. Then, the cardiomyocyte oxidative stress markers were measured. (A) Cardiomyocyte superoxide generation. (B) gp91^phox expression; top images: representative blots. The results are expressed as the mean±SEM of 8 separate experiments with triplicate samples for each experimental condition within each experiment. ^cP<0.01 vs the SIR group; ^fP<0.01 vs the SIR+BBR group; ⁱP<0.01 vs the SIR+BBR+JAK2 siRNA group.