Figure 2.

Elevated expression of Hsp27 is associated with poor prognosis in HCC patients. (A-B) Hsp27 expression was measured by western blotting and immunofluorescent analysis (scale bars, 10 µm) in one human normal liver cell line (L02) and a panel of HCC cell lines. (C) Typical images showed strong (+++), moderate (++), weak (+), or negative (-) staining of Hsp27 in HCC specimens. (D-E) Kaplan-Meier analysis of overall survival time and time to recurrence in 167 HCC cases based on Hsp27 expression.