Table 3.
Parasite clearance parameters by treatment arm
| Characteristics | AS+SP | AL |
|---|---|---|
| Total size (analyzed size for T1/2) | 24 (19) | 21 (16) |
| Parasite clearance half-life, T1/2 (hour)* | ||
| Median | 1.7 | 1.9 |
| IQR | 1.3–2.2 | 1.5–2.5 |
| Negative parasitemia at hour 24, % (n/N) | 73.9 (17/23) | 65.0 (13/20) |
| Day 2 positive parasitemia, % (n/N) | 0.0 (0/23) | 0.0 (0/20) |
| Day 3 positive parasitemia, % (n/N) | 0.0 (0/23) | 0.0 (0/20) |
| ACPR, % (n/N) | 100 (23/23) | 100 (20/20) |
ACPR = adequate clinical and parasitological response; AL = artemether + lumefantrine; AS+SP = artesunate + sulfadoxine–pyrimethamine; IQR = inter-quartile range. AS+SP vs. AL regarding negative parasitemia at hour 24, P = 0.53 (Pearson's χ2 test).
*
Those results are given by Worldwide Antimalarial Resistance Network's online parasite clearance estimator.