TABLE 2.

Inhibition of VIM variants by selected isoquinoline and pyridine-2-carboxylates

^a IC₅₀ determinations were performed in triplicate over a range of inhibitor concentrations from 0.2 to 2,000 μM. K_{D app} values were determined by ¹H CPMG NMR experiments (see Table S5 in the supplemental material).